C. Chun

Mapping and Engineering Antibody-Antigen Interaction Landscapes for Systematic Affinity Enhancement

The paper introduces a method to map antibody-antigen interactions using SPID platform to enhance affinity prediction and optimize antibody design.

Profiling multi-body interactions of BCL2 with single-molecule co-immunoprecipitation reveals the molecular mechanism of ABT-199 resistance

The paper uses single-molecule co-immunoprecipitation to profile BCL2 interactions with BH3-only proteins, revealing how mutations affect ABT-199 resistance through quantitative PPI data.

Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring.

This paper develops a fast, sensitive genetically encoded H2O2 sensor (oROS-G) and demonstrates its use in monitoring H2O2 dynamics in various cell types and models.

A High-Throughput Microfluidic Quantitative PCR Platform for the Simultaneous Quantification of Pathogens, Fecal Indicator Bacteria, and Microbial Source Tracking Markers

This study develops a microfluidic qPCR platform to simultaneously quantify pathogens, fecal indicators, and MST markers in water samples, revealing correlations between pathogens and human MST markers.

Spring-loaded inverted pendulum goes through two contraction-extension cycles during the single stance phase of walking

The paper shows that the spring-loaded inverted pendulum (SLIP) can model the single stance phase of walking but has limitations, leading to the development of a new model, ARSLIP, which accounts for active elements and contraction-extension cycles in the leg spring.