Author

C. Company

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

G. Gargiulo· 3 shared B. Jiang· 2 shared M. J. Schmitt· 2 shared M. Serresi· 2 shared Y. Dramaretska· 2 shared A. Tsankov· 1 shared B. Giotti· 1 shared D. Demircioglu· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBioengineering

G. Gargiulo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer

S. Mzoughi, M. Schwarz, X. Wang, D. Demircioglu, G. Ulukaya, K. Mohammed, F. Di Tullio, C. Company, Y. Dramaretska, M. Leushacke, B. Giotti, T. Lannagan, D. Lozano-Ojalvo, D. Hasson, A. Tsankov, , E. Guccione

This study identifies an oncofetal cell state that contributes to resistance in colorectal cancer and shows that targeting both this state and LGR5+ CSCs is needed for effective treatment.

bioRxiv · Dec 10, 2023Cancer Biology

Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses

B. Jiang, M. J. Schmitt, U. Rand, C. Company, M. Grossmann, M. Serresi, L. Cicin-Sain, G. Gargiulo

The paper identifies pharmacological modulators of epithelial immunity by analyzing SARS-CoV-2 infection responses using synthetic genetic reporters and drug screens.

bioRxiv · Nov 5, 2022Bioengineering

Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes

C. Company, M. J. Schmitt, Y. Dramaretska, S. Kertalli, B. Jiang, M. Serresi, I. Barozzi, G. Gargiulo

The paper introduces LSD, a computational framework for designing synthetic cis-regulatory DNA to mark cellular states, and demonstrates its effectiveness in identifying cell-state drivers.

bioRxiv · Nov 4, 2022Bioengineering