Author

E. Guccione

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

D. Lozano-Ojalvo· 2 shared A. Bertoletti· 1 shared A. C.-Y. Lee· 1 shared A. Garcia-Sastre· 1 shared A. J. Zhang· 1 shared A. Moreira· 1 shared A. Ortiz· 1 shared A. Tsankov· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

D. Lozano-Ojalvo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer

S. Mzoughi, M. Schwarz, X. Wang, D. Demircioglu, G. Ulukaya, K. Mohammed, F. Di Tullio, C. Company, Y. Dramaretska, M. Leushacke, B. Giotti, T. Lannagan, D. Lozano-Ojalvo, D. Hasson, A. Tsankov, , E. Guccione

This study identifies an oncofetal cell state that contributes to resistance in colorectal cancer and shows that targeting both this state and LGR5+ CSCs is needed for effective treatment.

bioRxiv · Dec 10, 2023Cancer Biology

RBFOX2 deregulation promotes pancreatic cancer metastasis through alternative splicing

M. Maurin, M. Ranjouri, K. Martin, R. Miner, J. Y. Newberg, D. Du, B. Centeno, J. B. Fleming, X. B. Yu, E. Guccione, M. Black, K. M. Mann

This study identifies RBFOX2 deregulation as a driver of pancreatic cancer metastasis through alternative splicing of ABI1, enhancing cancer cell stemness and invasiveness.

bioRxiv · Jun 1, 2022Cancer Biology

Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naive and COVID-19 recovered individuals

C. Camara, D. Lozano-Ojalvo, E. Lopez-Granados, E. Paz-Artal, M. Pion, R. Correa-Rocha, A. Ortiz, M. Lopez-Hoyos, M. Erro Iribarren, J. Portoles, P. Portoles, M. Perez-Olmeda, J. Oteo-Iglesias, C. Berin, E. Guccione, , J. Ochando

This study examines how the second dose of the BNT162b2 vaccine affects T cell immunity in naive and previously infected individuals, finding reduced cellular immunity in recovered individuals.

bioRxiv · Mar 22, 2021Immunology

Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.

J. S. Y. Ho, B. W.-Y. Mok, L. Campisi, T. Jordan, S. Yildiz, S. Parameswaran, J. A. Wayman, N. N. Gaudreault, D. A. Meekins, S. V. Indran, I. Morozov, J. D. Trujillo, Y. S. Fstkchyan, R. Rathnasinghe, Z. Zhu, , Jeya

This study shows that Top1 inhibition with Topotecan reduces SARS-CoV-2-induced inflammation and mortality in animal models.

bioRxiv · Dec 1, 2020 · PreprintMicrobiology