Author

C. Danussi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. T. Huse· 2 shared A. Rao· 1 shared E. P. Sulman· 1 shared G. J. Riggins· 1 shared J. Yang· 1 shared K. Kannan· 1 shared P. B. Malgulwar· 1 shared R. Shah· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

J. T. Huse

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2 papers

Recent·Most cited

Sirtuin 2 inhibition modulates chromatin landscapes genome- wide to induce senescence in ATRX-deficient malignant glioma

P. B. Malgulwar, C. Danussi, S. Dharmaiah, W. Johnson, A. Rao, J. T. Huse

This study shows that SIRT2 inhibition induces senescence in ATRX-deficient glioma models by altering chromatin landscapes and transcriptional profiles.

bioRxiv · Jan 9, 2023Cancer Biology

G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma

Y. Wang, J. Yang, W. H. Wu, R. Shah, C. Danussi, G. J. Riggins, K. Kannan, E. P. Sulman, T. A. Chan, J. T. Huse

This study shows ATRX deficiency in glioma causes genomic instability via G-quadruplex DNA, and G4 stabilization can be therapeutically targeted.

bioRxiv · Jun 14, 2018Cancer Biology