Author

C. de Freitas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 1

Frequent Co-Authors

A. Ferreira· 2 shared F. Bozza· 2 shared G. Barbosa-Lima· 2 shared M. Bastos· 2 shared M. Mattos· 2 shared N. Boechat· 2 shared P. Bozza· 2 shared P. Reis· 2 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. Ferreira

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2 papers

Recent·Most cited

Beyond members of the Flaviviridae family, sofosbuvir also inhibits chikungunya virus replication

A. Ferreira, P. Reis, C. de Freitas, C. Queiroz, L. Villas Boas Hoelz, M. Bastos, M. Mattos, E. Correia Loiola, P. Trindade, Y. Rangel Vieira, G. Barbosa-Lima, H. de Castro Faria Neto, N. Boechat, S. Rehen, K. Bruning, , T. Souza

This study shows sofosbuvir inhibits chikungunya virus replication in cell cultures and animal models, with selectivity over ribavirin and efficacy in vivo.

bioRxiv · Jul 2, 2018Microbiology

Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo

C. de Freitas, L. Higa, C. Sacramento, A. Ferreira, P. Reis, R. Delvecchio, F. Monteiro, G. Barbosa-Lima, Y. Vieira, M. Mattos, L. Hoelz, R. Leme, M. Bastos, F. Bozza, P. Bozza, , T. Souza

This study shows that sofosbuvir inhibits Yellow fever virus replication in vitro and protects mice from infection, suggesting it as a potential therapeutic option.

bioRxiv · Feb 15, 2018Microbiology