New mechanisms of radioiodide uptake revealed via a novel high throughput drug screening approach in thyroid cancer
M. L. Read, K. Brookes, C. E. M. Thornton, A. Fletcher, M. Alshahrani, R. Khan, H. R. Nieto, P. Borges de Souza, J. R. M. Webster, L. J. Alderwick, K. Boelaert, V. E. Smith, C. J. McCabe
This study identifies FDA-approved drugs that enhance radioiodide uptake through non-canonical NIS processing pathways, revealing new therapeutic strategies for thyroid cancer.
bioRxiv · Jul 21, 2020 · PreprintCancer Biology