Author

C. E. MacPhee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:bacteria (other)· 5 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

R. J. Morris· 4 shared T. Sukhodub· 4 shared M. Schor· 3 shared N. R. Stanley-Wall· 3 shared A. S. Ferreira· 2 shared C. Earl· 2 shared K. M. Bromley· 2 shared N. Stanley-Wall· 2 shared

Activity by Year

2016-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersMicrobiology

R. J. Morris

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Author profile →

6 papers

Recent·Most cited

Lipid-induced polymorphic amyloid fibrils formation by α-synuclein.

B. P. Singh, R. J. Morris, M. H. Horrocks, T. Kunath, C. E. MacPhee

This study shows that lipid membranes accelerate α-synuclein aggregation and promote the formation of diverse polymorphic amyloid fibrils, which may contribute to Parkinson's disease pathology.

bioRxiv · Jul 20, 2021Biophysics

Founder cell configuration drives competitive outcome within colony biofilms

L. Eigentler, M. Kalamara, G. Ball, C. E. MacPhee, N. R. Stanley-Wall, F. A. Davidson

The paper shows that founder cell location and density determine competitive outcomes in biofilms, with spatial dynamics being the main driver of strain abundance.

bioRxiv · Jul 8, 2021Microbiology

Density and temperature controlled fluid extraction in a bacterial biofilm is determined by poly-γ-glutamic acid production

R. J. Morris, T. Sukhodub, C. E. MacPhee, N. R. Stanley-Wall

This study shows that PGA production in B. subtilis NCIB 3610 biofilms is temperature-dependent and drives fluid extraction, influencing biofilm morphology and motility.

bioRxiv · Dec 21, 2020Microbiology

Formation of functional, non-amyloidogenic fibres by recombinant Bacillus subtilis TasA

E. Erskine, R. Morris, M. Schor, C. Earl, R. M. C. Gillespie, K. Bromley, T. Sukhodub, L. Clark, P. Fyfe, L. Serpell, N. Stanley-Wall, C. E. MacPhee

This paper shows recombinant Bacillus subtilis TasA forms functional, non-amyloidogenic fibres with properties similar to native fibres, revealing species-specific biofilm matrix assembly requirements.

bioRxiv · Apr 18, 2018Microbiology

Bifunctionality Of A Biofilm Matrix Protein Controlled By Redox State

S. Arnaouteli, A. S. Ferreira, M. Schor, R. J. Morris, K. M. Bromley, J. K. Jo, K. L. Cortez, T. Sukhodub, A. R. Prescott, L. E. P. Dietrich, C. E. MacPhee, N. Stanley-Wall

This study shows that BslA, a biofilm matrix protein in Bacillus subtilis, has two distinct functions controlled by redox state and dimerization.

bioRxiv · May 15, 2017Microbiology

Evolutionary variations in the biofilm-associated protein BslA from the genus Bacillus

R. J. Morris, M. Schor, R. M. C. Gillespie, A. S. Ferreira, K. M. Bromley, L. Baldauf, S. Arnaouteli, T. Sukhodub, A. Ostrowski, L. Hobley, C. Earl, N. R. Stanley-Wall, C. E. MacPhee

The paper characterizes BslA orthologues and a paralogue from different Bacillus species, showing functional substitution and correlating biophysical properties with function.

bioRxiv · Dec 12, 2016Microbiology