Author

T. Kunath

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 3 Research Focus:clustering· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

N. J. Drummond· 2 shared A. Chai· 1 shared A. Dadvar· 1 shared A. Gandhi· 1 shared A. Natalwala· 1 shared A. Rosenstein· 1 shared B. Murareanu· 1 shared B. P. Singh· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

N. J. Drummond

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

FAST-STEM: A human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices

A. Rosenstein, R. Sambathkumar, B. Murareanu, N. Dhaliwal, F. Sun, X. Zhao, A. Dadvar, R. Al-attar, A. Chai, N. Gulati, T. Yin, M. Nguyen, D. Serra, T. Devina, A. Gandhi, , M. J. Garton

FAST-STEM accelerates human pluripotent stem cell engineering by enabling rapid transgene integration and differentiation into multiple cell types.

bioRxiv · May 23, 2024 · PreprintBioengineering

An isogenic collection of pluripotent stem cell lines with elevated α-synuclein expression

A. Natalwala, R. Behbehani, R. Yapom, T. Kunath

The paper generates isogenic human embryonic stem cell lines with varying levels of α-synuclein expression to study its impact on neuronal differentiation in Parkinson's and Lewy body diseases.

bioRxiv · Feb 10, 2022 · PreprintCell Biology

Lipid-induced polymorphic amyloid fibrils formation by α-synuclein.

B. P. Singh, R. J. Morris, M. H. Horrocks, T. Kunath, C. E. MacPhee

This study shows that lipid membranes accelerate α-synuclein aggregation and promote the formation of diverse polymorphic amyloid fibrils, which may contribute to Parkinson's disease pathology.

bioRxiv · Jul 20, 2021Biophysics

Cryopreservation of midbrain dopaminergic neural cells differentiated from human embryonic stem cells

N. J. Drummond, K. S. Dolt, M. A. Canham, P. Kilbride, G. J. Morris, T. Kunath

This paper compares cryopreservation media and conditions for midbrain dopaminergic neural precursor cells derived from human embryonic stem cells, finding optimal conditions that maximize viability and maintain differentiation potential.

bioRxiv · Feb 11, 2020Cell Biology

A novel mitochondrial enriched antioxidant protects neurons against acute oxidative stress

N. J. Drummond, N. O. Davies, J. E. Lovett, M. R. Miller, G. Cook, T. Becker, C. G. Becker, D. B. McPhail, T. Kunath

This study identifies Proxison, a novel flavonoid antioxidant, showing enhanced neuroprotection against oxidative stress in vitro and in a zebrafish model.

bioRxiv · Feb 17, 2017Cell Biology