Author

C. Escrevente

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1

Frequent Co-Authors

D. C. Barral· 3 shared M. C. Seabra· 3 shared L. B. Lopes· 2 shared M. J. Hall· 2 shared M. V. Neto· 2 shared A. C. Fradinho· 1 shared A. S. Falcao· 1 shared C. E. Futter· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

D. C. Barral

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Author profile →

4 papers

Recent·Most cited

Photoprotective melanin is maintained within keratinocytes in a storage lysosome

M. V. Neto, M. J. Hall, J. Charneca, C. Escrevente, M. C. Seabra, D. C. Barral

The paper shows melanin-containing phagosomes in keratinocytes mature into storage lysosomes called melanokerasomes, which retain melanin for long-term photoprotection.

bioRxiv · Feb 5, 2024Cell Biology

FORMATION OF LIPOFUSCIN-LIKE AUTOFLUORESCENT GRANULES IN THE RETINAL PIGMENT EPITHELIUM REQUIRES LYSOSOME DYSFUNCTION

C. Escrevente, A. S. Falcao, M. J. Hall, M. Lopes-da-Silva, P. Antas, M. M. Mesquita, I. S. Ferreira, M. H. Cardoso, A. C. Fradinho, C. E. Futter, S. Tenreiro, M. C. Seabra

This study shows that lysosomal dysfunction leads to incomplete degradation of photoreceptor outer segments and accumulation of autofluorescent granules in RPE cells.

Investigative Opthalmology & Visual Science · Jul 27, 2021Peer-reviewedCell Biology

Melanocore uptake by keratinocytes occurs through phagocytosis and involves Protease-activated receptor-2 activation

H. Moreiras, M. V. Neto, L. B. Lopes, C. Escrevente, J. S. Ramalho, M. C. Seabra, D. C. Barral

The paper investigates how melanocores and melanosomes are internalized by keratinocytes, finding that melanocores are taken up via phagocytosis involving PAR-2 activation, while melanosomes use macropinocytosis.

bioRxiv · Apr 13, 2021 · PreprintCell Biology

A novel Rab11-Rab3a cascade required for lysosome exocytosis

C. Escrevente, L. B. Lopes, J. Ramalho, D. C. Barral

The paper identifies a Rab11-Rab3a cascade that regulates lysosome exocytosis through interactions involving Rab11, GRAB, and Sec15.

bioRxiv · Mar 6, 2021 · PreprintCell Biology