Author

C. E. Futter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Assay:electronic health records· 1 Organism:mouse· 1

Frequent Co-Authors

M. C. Seabra· 2 shared T. Burgoyne· 2 shared A. C. Fradinho· 1 shared A. H. Futerman· 1 shared A. L. Pinto· 1 shared A. Peden· 1 shared A. S. Falcao· 1 shared A. Shah· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

M. C. Seabra

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

FORMATION OF LIPOFUSCIN-LIKE AUTOFLUORESCENT GRANULES IN THE RETINAL PIGMENT EPITHELIUM REQUIRES LYSOSOME DYSFUNCTION

C. Escrevente, A. S. Falcao, M. J. Hall, M. Lopes-da-Silva, P. Antas, M. M. Mesquita, I. S. Ferreira, M. H. Cardoso, A. C. Fradinho, C. E. Futter, S. Tenreiro, M. C. Seabra

This study shows that lysosomal dysfunction leads to incomplete degradation of photoreceptor outer segments and accumulation of autofluorescent granules in RPE cells.

Investigative Opthalmology & Visual Science · Jul 27, 2021Peer-reviewedCell Biology

Ultrastructural insight into SARS-CoV-2 attachment, entry and budding in human airway epithelium

A. L. Pinto, R. K. Rai, J. C. Brown, P. Griffin, J. R. Edgar, A. Shah, A. Singanayagam, C. Hogg, W. S. Barclay, C. E. Futter, T. Burgoyne

This study uses electron microscopy to examine SARS-CoV-2 infection in human airway epithelium, showing viral entry through the plasma membrane and budding from intracellular compartments.

bioRxiv · Apr 10, 2021 · PreprintMicrobiology

Cholesteryl Hemiazelate Induces Lysosome Dysfunction and Exocytosis in Macrophages

N. Domingues, R. D. A. Calado, P. Brito, R. Matthiesen, J. Ramalho, M. I. L. Soares, T. Pereira, L. Oliveira, J. Vicente, L. H. Wong, S. M. Cho, I. Simoes, J. Sampaio, C. Klose, M. A. Surma, , O. V. Vieira

This study identifies cholesteryl hemiazelate as a cause of lysosome dysfunction and exocytosis in macrophages, contributing to atherosclerosis.

bioRxiv · Jan 5, 2021 · PreprintCell Biology

Symmetric arrangement of mitochondria:plasma membrane contacts between adjacent photoreceptor cells regulated by Opa1

I. P. Meschede, M. C. Seabra, C. E. Futter, M. Votruba, M. E. Cheetham, T. Burgoyne

The paper examines the specialized arrangement of mitochondria in photoreceptor inner segments and shows that Opa1 regulates their contact with the plasma membrane.

bioRxiv · May 21, 2019Cell Biology