O-GlcNAcylation of small heat shock proteins enhances their anti-amyloid chaperone activity
A. T. Balana, P. M. Levine, S. Mukherjee, N. J. Pedowitz, S. P. Moon, T. T. Takahashi, C. F. W. Becker, M. R. Pratt
This study shows that O-GlcNAcylation enhances the anti-amyloid activity of small heat shock proteins by modulating their interaction with substrates.
bioRxiv · Dec 10, 2019Biochemistry