Author

A. T. Balana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Assay:protein structure· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

M. R. Pratt· 2 shared A. Javed· 1 shared A.-L. Mahul-Mellier· 1 shared B. A. Nguyen· 1 shared C. F. W. Becker· 1 shared E. R. Hard· 1 shared H. A. Lashuel· 1 shared K. C. Luk· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

M. R. Pratt

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Author profile →

2 papers

Recent·Most cited

O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology

A. T. Balana, A.-L. Mahul-Mellier, B. A. Nguyen, M. Horvath, A. Javed, E. R. Hard, Y. Jasiqi, P. Singh, S. Afrin, R. Pedretti, V. Singh, V. M.-Y. Lee, K. C. Luk, L. Saelices, H. A. Lashuel, M. R. Pratt

This study shows that O-GlcNAc modification of α-Synuclein leads to amyloid fibrils with reduced seeding activity and pathology in Parkinson's disease models.

bioRxiv · Mar 7, 2023 · PreprintBiochemistry

O-GlcNAcylation of small heat shock proteins enhances their anti-amyloid chaperone activity

A. T. Balana, P. M. Levine, S. Mukherjee, N. J. Pedowitz, S. P. Moon, T. T. Takahashi, C. F. W. Becker, M. R. Pratt

This study shows that O-GlcNAcylation enhances the anti-amyloid activity of small heat shock proteins by modulating their interaction with substrates.

bioRxiv · Dec 10, 2019Biochemistry