Author

N. J. Pedowitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. R. Pratt· 2 shared A. R. Batt· 1 shared A. T. Balana· 1 shared C. F. W. Becker· 1 shared E. C. Woods· 1 shared J. Jaworek-Korjakowska· 1 shared J. Jo· 1 shared K. W. Park· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

M. R. Pratt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of S. aureus Infections

J. Jo, T. Upadhyay, E. C. Woods, K. W. Park, N. J. Pedowitz, J. Jaworek-Korjakowska, S. Wang, T. A. Valdez, M. Fellner, M. Bogyo

The paper develops oxadiazolone-based probes targeting FphE to specifically detect S. aureus infections through covalent modification of the enzyme's active site.

bioRxiv · Dec 11, 2023 · PreprintMicrobiology

MYPT1 O-GlcNAc modification controls the sensitivity of fibroblasts to sphingosine-1-phosphate mediated cellular contraction

N. J. Pedowitz, A. R. Batt, N. Darabedian, M. R. Pratt

This study shows that MYPT1 O-GlcNAc modification regulates fibroblast sensitivity to S1P-induced contraction by inhibiting MYPT1 phosphorylation and MLC dephosphorylation, impacting wound healing.

bioRxiv · Jun 24, 2020 · PreprintCell Biology

O-GlcNAcylation of small heat shock proteins enhances their anti-amyloid chaperone activity

A. T. Balana, P. M. Levine, S. Mukherjee, N. J. Pedowitz, S. P. Moon, T. T. Takahashi, C. F. W. Becker, M. R. Pratt

This study shows that O-GlcNAcylation enhances the anti-amyloid activity of small heat shock proteins by modulating their interaction with substrates.

bioRxiv · Dec 10, 2019Biochemistry