PathologybioRxiv
Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies
D. Brayson, A. Frustaci, R. Verardo…·C. M. Shanahan
This study shows prelamin A accumulation drives inflammation in both inherited and acquired cardiomyopathies, suggesting potential treatment strategies targeting inflammation.
DOI 10.1172/jci.insight.126315