Author

C. G. Shuttle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

D. Stamou· 2 shared A. Breuer· 1 shared A. Gupta· 1 shared A. Tonnesen· 1 shared C. G. Tate· 1 shared E. Kazepidou· 1 shared E. KOSMIDIS· 1 shared G. Kockelkoren· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

D. Stamou

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Author profile →

2 papers

Recent·Most cited

Multimodal intrinsic activation of GPCRs in ultrastable plasma membrane nanodomains

G. Kockelkoren, J. Carstensen, L. Lauritsen, E. Kazepidou, A. Tonnesen, C. G. Shuttle, P. S. Kaas, A. Gupta, A. Breuer, S. G. F. Rasmussen, L. Duffet, T. Warne, T. Patriarchi, C. G. Tate, M. Uline, D. Stamou

This paper quantifies GPCR intrinsic activation at the plasma membrane, revealing spatial multimodality with most receptors showing negligible spontaneous activation.

bioRxiv · Feb 28, 2024 · PreprintBiophysics

Regulation of the mammalian-brain V-ATPase via ultra-slow mode-switching

E. KOSMIDIS, C. G. Shuttle, J. Preobraschenski, M. Ganzella, P. J. Johnson, S. Veshaguri, M. P. Moeller, O. Marantos, J. L. Pedersen, R. Jahn, D. Stamou

This study shows mammalian-brain V-ATPases switch between proton-pumping, inactive, and proton-leaky modes, with ATP regulating mode-switching probability rather than pumping rate.

bioRxiv · Oct 6, 2022 · PreprintBiophysics