Author

L. Lauritsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:fluorescence / live-cell microscopy· 2 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

M. Szomek· 2 shared A. Breuer· 1 shared A. D. Juhl· 1 shared A. Gupta· 1 shared A. J. Foster· 1 shared A. Tonnesen· 1 shared B. Poolman· 1 shared C. G. Shuttle· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

M. Szomek

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ratiometric fluorescence nanoscopy and lifetime imaging of novel Nile Red analogs for analysis of membrane packing in living cells

L. Lauritsen, M. Szomek, M. Hornum, P. Reinholdt, J. Kongsted, P. Nielsen, J. R. Brewer, D. Wustner

This study evaluates modified Nile Red dyes for super-resolution imaging of membrane packing in cells, finding differences in membrane structure between healthy and NPC1 disease fibroblasts.

Scientific Reports · Jun 14, 2024Peer-reviewedBiophysics

Multimodal intrinsic activation of GPCRs in ultrastable plasma membrane nanodomains

G. Kockelkoren, J. Carstensen, L. Lauritsen, E. Kazepidou, A. Tonnesen, C. G. Shuttle, P. S. Kaas, A. Gupta, A. Breuer, S. G. F. Rasmussen, L. Duffet, T. Warne, T. Patriarchi, C. G. Tate, M. Uline, D. Stamou

This paper quantifies GPCR intrinsic activation at the plasma membrane, revealing spatial multimodality with most receptors showing negligible spontaneous activation.

bioRxiv · Feb 28, 2024 · PreprintBiophysics

Ergosterol mediates aggregation of natamycin in the yeast plasma membrane

M. Szomek, V. Akkerman, L. Lauritsen, H.-L. Walther, A. D. Juhl, K. Thaysen, J. M. Egebjerg, D. F. Covey, M. Lehmann, P. Wessig, A. J. Foster, B. Poolman, S. Werner, G. Schneider, P. Müller, D. Wüstner

This paper shows that ergosterol mediates natamycin aggregation in yeast plasma membranes, which underlies its antifungal activity and can be enhanced by sphingolipid inhibitors.

bioRxiv · Dec 5, 2023 · PreprintBiophysics