Author

C. H. Lipper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

S. C. Blacklow· 2 shared A. N. Dates· 1 shared D. T. D. Jones· 1 shared E. D. Egan· 1 shared K.-H. Gabriel· 1 shared M. M. Burruss· 1 shared S. D. Rawson· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

S. C. Blacklow

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Author profile →

2 papers

Recent·Most cited

Structural Basis for Selective Proteolysis of ADAM10 Substrates at Membrane-Proximal Sites

C. H. Lipper, E. D. Egan, K.-H. Gabriel, S. C. Blacklow

This study determines the cryo-EM structure of ADAM10-Tspan15 complex, revealing how Tspan15 relieves autoinhibition and positions the active site for membrane-proximal substrate cleavage.

bioRxiv · Oct 22, 2022 · PreprintBiochemistry

Tethered agonist activated ADGRF1 structure reveals molecular preference for Gq signaling

D. T. D. Jones, A. N. Dates, S. D. Rawson, M. M. Burruss, C. H. Lipper, S. C. Blacklow

The paper reports the cryo-EM structure of ADGRF1, revealing structural features that explain its preference for Gq signaling over Gs.

bioRxiv · Sep 9, 2022 · PreprintBiochemistry