Tethered agonist activated ADGRF1 structure reveals molecular preference for Gq signaling
D. T. D. Jones, A. N. Dates, S. D. Rawson, M. M. Burruss, C. H. Lipper, S. C. Blacklow
The paper reports the cryo-EM structure of ADGRF1, revealing structural features that explain its preference for Gq signaling over Gs.
bioRxiv · Sep 9, 2022 · PreprintBiochemistry