Author

C. H.-J. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Simmons· 3 shared H. Koohy· 3 shared A. Antanaviciute· 2 shared J. Woo· 2 shared P. Buckley· 2 shared D. S. Shcherbinin· 1 shared G. Ogg· 1 shared I. Woodhouse· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

A. Simmons

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3 papers

Recent·Most cited

A systems approach evaluating the impact of SARS-CoV-2 variant of concern mutations on CD8+ T cell responses

P. R. Buckley, C. H.-J. Lee, A. Antanaviciute, A. Simmons, H. Koohy

This study evaluates how SARS-CoV-2 variant mutations affect CD8+ T cell responses using immunogenicity scores and in-silico mutagenesis.

bioRxiv · Oct 21, 2022 · PreprintImmunology

HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronaviruses

P. Buckley, C. H.-j. Lee, M. P. Pinho, R. O. Babu, J. Woo, A. Antanaviciute, A. Simmons, G. Ogg, H. Koohy

This study identifies SARS-CoV-2 peptides with cross-reactivity to human coronaviruses and shows that TCR repertoires in COVID-19 patients are HLA-dependent.

bioRxiv · Jul 17, 2021Immunology

Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens

P. Buckley, R. Ma, C. H.-J. Lee, I. Woodhouse, J. Woo, V. O. Tsvetkov, D. S. Shcherbinin, M. Shugay, M. Rei, A. Simmons, H. Koohy

This study evaluates existing computational models for predicting CD8+ T cell epitopes and cancer neoantigens, finding poor performance for emerging viruses and cancer peptides.

bioRxiv · Dec 25, 2020Immunology