Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens
P. Buckley, R. Ma, C. H.-J. Lee, I. Woodhouse, J. Woo, V. O. Tsvetkov, D. S. Shcherbinin, M. Shugay, M. Rei, A. Simmons, H. Koohy
This study evaluates existing computational models for predicting CD8+ T cell epitopes and cancer neoantigens, finding poor performance for emerging viruses and cancer peptides.
bioRxiv · Dec 25, 2020Immunology