Focal adhesion-generated cues in extracellular matrix regulate cell migration by local induction of clathrin-coated plaques
D. Bucher, M. Mukenhirn, K. A. Sochacki, V. Saharuka, C. Huck, C. Zambarda, j. Taraska, E. A. Cavalcanti-Adam, S. Boulant
This study identifies Eps15 and Eps15R as key regulators of clathrin-coated plaque formation, linking ECM remodeling by focal adhesions to cell migration directionality.
bioRxiv · Dec 11, 2018 · PreprintCell Biology