Author

C. Insinna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Organism:zebrafish· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

A. C. Burrows· 1 shared A. E. Torres· 1 shared A. G. Stephen· 1 shared A. S. Dickson· 1 shared B. A. Link· 1 shared B. R. Stromberg· 1 shared C. Agamasu· 1 shared C. J. Westlake· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A. C. Burrows

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

RASopathy Mutations Provide Functional Insight into the BRAF Cysteine-rich Domain and Demonstrate the Importance of Autoinhibition in BRAF Regulation

R. Spencer-Smith, E. M. Terrell, C. Insinna, C. Agamasu, M. E. Wagner, D. A. Ritt, J. Stauffer, A. G. Stephen, D. K. Morrison

This study examines RASopathy mutations in the BRAF cysteine-rich domain, showing they increase BRAF activity by relieving autoinhibition and enhancing PS binding, with autoinhibition being the main factor affecting mutation severity.

bioRxiv · Oct 1, 2021Cell Biology

The Deubiquitinating Enzyme USP37 Stabilizes CHK1 to Promote the Cellular Response to Replication Stress

M. Singh, A. C. Burrows, A. E. Torres, D. Pal, B. R. Stromberg, C. Insinna, A. S. Dickson, C. J. Westlake, M. K. Summers

This study shows that USP37 stabilizes CHK1 to enhance the cellular response to replication stress, revealing a new role for USP37 beyond S-phase entry.

bioRxiv · May 29, 2019Cell Biology

Kif17 phosphorylation regulates its ciliary localization and photoreceptor outer segment turnover

T. R. Lewis, S. R. Kundinger, B. A. Link, C. Insinna, J. C. Besharse

This study shows that phosphorylation of KIF17 enhances its ciliary localization and promotes photoreceptor outer segment turnover through disc shedding.

bioRxiv · Jun 20, 2018Cell Biology