Author

C. J. Knoot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. M. Harding· 3 shared D. A. Rosen· 3 shared P. L. Wantuch· 3 shared E. Vinogradov· 2 shared L. S. Robinson· 2 shared A. S. Cross· 1 shared B. Bernshtein· 1 shared D. J. Roach· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

C. M. Harding

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Antibody responses in Klebsiella pneumoniae bloodstream infection: a cohort study

W. Hwang, P. L. Wantuch, B. Bernshtein, J. Zhiteneva, D. Slater, K. H. Vater, S. Sridhar, E. Oliver, D. J. Roach, S. Rao, S. E. Turbett, C. J. Knoot, C. M. Harding, M. N. Amin, A. S. Cross, , J. B. Harris

This study examines antibody responses to Klebsiella pneumoniae OPS antigens in bloodstream infections, finding high immunogenicity and cross-reactivity but also capsule-mediated inhibition of antibody function.

bioRxiv · May 1, 2024 · PreprintMicrobiology

A heptavalent O-antigen bioconjugate vaccine exhibits differential functional antibody responses against diverse Klebsiella pneumoniae isolates

P. L. Wantuch, C. J. Knoot, L. S. Robinson, E. Vinogradov, N. Scott, C. M. Harding, D. A. Rosen

This study develops a heptavalent O-antigen vaccine against Klebsiella pneumoniae, showing varying efficacy against different isolates.

bioRxiv · Dec 12, 2023 · PreprintImmunology

Capsular polysaccharide inhibits vaccine-induced O-antigen antibody binding and function across both classical and hypervirulent K2:O1 strains of Klebsiella pneumoniae

P. L. Wantuch, C. J. Knoot, L. S. Robinson, E. Vinogradov, N. E. Scott, C. M. Harding, D. A. Rosen

This study compares two vaccines targeting K. pneumoniae: one against capsular polysaccharide and one against O-antigen, finding that capsule inhibits O-antigen antibody function and that the capsule vaccine is more effective.

PLOS Pathogens · May 5, 2023Peer-reviewedMicrobiology