C. K. Mirth

Fluctuating temperatures exacerbate nutritional stress during development in Drosophila melanogaster

This study shows that fluctuating temperatures worsen nutritional stress in Drosophila populations, with tropical populations more affected than temperate ones.

Short-term fasting of a single amino acid extends lifespan.

Short-term isoleucine deprivation in Drosophila extends lifespan and improves toxin resistance, with benefits dependent on timing and duration of deprivation.

Identifying the proximate mechanisms that generate variation in nutritional plasticity for fecundity in Drosophila melanogaster

This study identifies that genetic variation in fecundity plasticity in Drosophila melanogaster is due to differences in food intake and conversion efficiency, not morphology.

Ageing impairs protein leveraging in a sex-specific manner in Drosophila melanogaster

This study shows that young Drosophila melanogaster exhibit sex-specific differences in protein leveraging, with females varying carbohydrate intake more than males, and these behaviors decline with age, especially in females.

A dietary sterol trade off determines lifespan responses to dietary restriction in Drosophila melanogaster

This study shows that dietary sterol partitioning between reproduction and lifespan, rather than macronutrients themselves, determines lifespan extension in Drosophila under dietary restriction.

When does diet matter? The roles of larval and adult nutrition in regulating adult size traits.

This study investigates how larval and adult nutrition affect adult body size traits in Drosophila melanogaster, finding larval diet has greater impacts and macronutrient restriction is more detrimental than caloric restriction.