Mapping the Immunodominance Landscape of SARS-CoV-2 Spike Protein for the Design of Vaccines against COVID-19
B.-z. Zhang, Y.-f. Hu, L.-l. Chen, Y.-g. Tong, J.-c. Hu, J.-p. Cai, K.-H. Chan, Y. Dou, J. Deng, H.-r. Gong, C. Kuwentrai, W. Li, X.-l. Wang, H. Chu, C.-h. Su, , J.-D. Huang
This study maps immunodominant sites on the SARS-CoV-2 spike protein using patient sera to identify potential vaccine candidates and demonstrates their neutralizing activity in mice.
bioRxiv · Apr 23, 2020 · PreprintMicrobiology