Author

I. F.-N. Hung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:statistical model· 1

Frequent Co-Authors

K. K.-W. To· 3 shared B.-Z. Zhang· 2 shared H. Chu· 2 shared H.-R. Gong· 2 shared J.-c. Hu· 2 shared J.-D. Huang· 2 shared J.-P. Cai· 2 shared K. Y. Yuen· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersImmunology

K. K.-W. To

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Three-dose vaccination-induced immune responses protect against SARS-CoV-2 Omicron-BA.2

R. Zhou, N. Liu, X. Li, Q. Peng, C.-K. Yiu, H. Huang, D. Yang, Z. Du, H.-Y. Kwok, K.-K. Au, J.-P. Cai, I. F.-N. Hung, K. K.-W. To, X. Xu, K.-Y. Yuen, Z. Chen

This study evaluates the effectiveness of three-dose SARS-CoV-2 vaccination against Omicron BA.2 breakthrough infections and finds that third-dose vaccination significantly reduces infection rates and severity.

bioRxiv · May 9, 2022 · PreprintImmunology

Computation of Antigenicity Predicts SARS-CoV-2 Vaccine Breakthrough Variants

Y.-f. Hu, J.-c. Hu, H.-R. Gong, A. Danchin, R. Sun, H. Chu, I. F.-N. Hung, K. Y. Yuen, K. K.-W. To, B.-Z. Zhang, T. Yau, J.-D. Huang

This paper develops a computational model to predict SARS-CoV-2 variant antigenicity from sequence data, showing high accuracy in predicting neutralisation titre decreases for known variants and Omicron.

bioRxiv · Jan 19, 2022Evolutionary Biology

Mapping the Immunodominance Landscape of SARS-CoV-2 Spike Protein for the Design of Vaccines against COVID-19

B.-z. Zhang, Y.-f. Hu, L.-l. Chen, Y.-g. Tong, J.-c. Hu, J.-p. Cai, K.-H. Chan, Y. Dou, J. Deng, H.-r. Gong, C. Kuwentrai, W. Li, X.-l. Wang, H. Chu, C.-h. Su, , J.-D. Huang

This study maps immunodominant sites on the SARS-CoV-2 spike protein using patient sera to identify potential vaccine candidates and demonstrates their neutralizing activity in mice.

bioRxiv · Apr 23, 2020 · PreprintMicrobiology