Author

C. L. Chavez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. C. Berk· 2 shared C. G. Hsu· 2 shared M. Sowden· 2 shared C. Yan· 1 shared C. Zhang· 1 shared W. Li· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

B. C. Berk

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2 papers

Recent·Most cited

Pnpt1 mediates NLRP3 inflammasome activation by MAVS and metabolic reprogramming in macrophages

C. G. Hsu, W. Li, M. Sowden, C. L. Chavez, B. C. Berk

This study shows that Pnpt1 mediates NLRP3 inflammasome activation in macrophages through MAVS and metabolic reprogramming, enhancing IL-1β and IL-18 secretion in sepsis models.

bioRxiv · May 7, 2022Immunology

The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis

C. G. Hsu, C. L. Chavez, C. Zhang, M. Sowden, C. Yan, B. C. Berk

This study shows that 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis in models of acute lung injury and sepsis.

bioRxiv · Feb 1, 2022Immunology