Author

C. L. Johnston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. M. van Oijen· 2 shared H. Ecroyd· 2 shared N. R. Marzano· 2 shared B. P. Paudel· 1 shared B. Paudel· 1 shared G. Wright· 1 shared J. L. P. Benesch· 1 shared K. M. Wray· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

A. M. van Oijen

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2 papers

Recent·Most cited

An α-cyanostilbene derivative for the enhanced detection and imaging of amyloid fibril aggregates

N. R. Marzano, K. M. Wray, C. L. Johnston, B. P. Paudel, Y. Hong, A. M. van Oijen, H. Ecroyd

This paper introduces ASCP, a fluorescent probe with enhanced sensitivity and specificity for detecting amyloid fibrils and oligomeric intermediates compared to ThT.

bioRxiv · Jun 25, 2020Biochemistry

Single-molecule fluorescence-based approach reveals novel mechanistic insights into small heat shock protein chaperone function

C. L. Johnston, N. R. Marzano, B. Paudel, G. Wright, J. L. P. Benesch, A. M. van Oijen, H. Ecroyd

This study uses single-molecule fluorescence to reveal a two-step mechanism by which human Bc (HSPB5) interacts with misfolded proteins to prevent aggregation.

bioRxiv · Feb 16, 2020Biochemistry