Author

C. Lourenco

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

J. De Melo· 1 shared J. Longo· 1 shared K. E. Houlahan· 1 shared L. Z. Penn· 1 shared M. Kalkat· 1 shared P. C. Boutros· 1 shared S. J. Done· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

J. De Melo

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1 paper

Recent·Most cited

Modeling the MYC-driven normal-to-tumour switch in breast cancer.

C. Lourenco, M. Kalkat, K. E. Houlahan, J. De Melo, J. Longo, S. J. Done, P. C. Boutros, L. Z. Penn

This study creates an in vivo model of MYC-driven breast cancer by combining PIK3CAH1047R mutation with deregulated MYC, showing a normal-to-tumour switch and dependence on MYC for tumor growth.

bioRxiv · Aug 20, 2018Cancer Biology