Mechanistic basis for SNX27-Retromer coupling to ESCPE-1 in promoting endosomal cargo recycling.
B. Simonetti, Q. Guo, M. Gimenez-Andres, K.-E. Chen, E. R. R. Moody, A. J. Evans, C. M. Danson, T. A. Williams, B. M. Collins, P. J. Cullen
This study identifies the molecular mechanism by which SNX27-Retromer interacts with ESCPE-1 to facilitate endosomal cargo recycling, revealing a conserved surface interaction and evolutionary pathway.
bioRxiv · Aug 28, 2021 · PreprintCell Biology