Author

C. M. Polonio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. P. S. Peron· 3 shared L. G. Oliveira· 3 shared N. G. Zanluqui· 3 shared J. L. Proenca-Modena· 2 shared M. G. Oliveira· 2 shared M. P. Cunha· 2 shared M. R. Amorim· 2 shared S. P. Muraro· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersImmunology

J. P. S. Peron

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells

L. M. Sanmarco, J. M. Rone, C. M. Polonio, F. Giovannoni, G. Fernandez Lahore, K. Ferrara, C. Gutierrez-Vazquez, N. Li, A. Sokolovska, A. Plasencia, C. Faust Akl, P. Nanda, E. S. Heck, Z. Li, H.-G. Lee, , F. J. Quintana

The paper identifies an immunometabolic pathway in dendritic cells that limits autoimmunity and develops a synthetic probiotic to activate this pathway.

bioRxiv · Mar 17, 2023 · PreprintImmunology

SARS-CoV-2 Infection Impacts Carbon Metabolism and Depends on Glutamine for Replication in Syrian Hamster Astrocytes

L. G. Oliveira, Y. d. S. Angelo, P. Yamamoto, V. C. Carregari, F. Crunfli, G. Reis-de-Oliveira, L. Costa, E. A. Duque, N. B. Santos, G. M. Almeida, E. M. S. Firmino, I. M. Paiva, C. M. Polonio, N. G. Zanluqui, M. G. Oliveira, , J. P. S. Peron

This study shows SARS-CoV-2 infection alters carbon metabolism in hamster astrocytes, with glutamine dependency for replication and links to neurological symptoms.

bioRxiv · Oct 23, 2021Immunology

Zika Virus Infection of Murine and Human Neutrophils and their Function as Trojan Horses to the Placenta

N. G. Zanluqui, L. G. Oliveira, C. M. Polonio, T. T. Franca, G. S. Fabiano, S. P. Muraro, M. R. Amorim, V. C. Carregari, C. Brandao-Teles, P. da Silva, M. G. Oliveira, R. F. Oliveira-Franca, M. P. Cunha, M. Nogueira, D. M. Souza, , J. P. S. Peron

This study shows that neutrophils support ZIKV infection and may facilitate vertical transmission by acting as trojan horses to the placenta.

bioRxiv · Sep 14, 2021 · PreprintImmunology

Gas6 drives Zika virus-induced neurological complications in humans and congenital syndrome in immunocompetent mice

J. L. Silva-Filho, The Zika-Unicamp Network, L. G. Oliveira, L. Monteiro, P. L. Parise, N. G. Zanluqui, C. M. Polonio, C. L. Freitas, D. A. Toledo-Teixeira, W. M. Souza, N. Bittencourt, M. R. Amorim, J. Forato, S. P. Muraro, G. F. Souza, , J. L. Proenca-Modena

This study shows Gas6 promotes ZIKV replication and severity in humans and mice, linking it to neurological complications and congenital malformations.

bioRxiv · Jan 27, 2021Microbiology