Author

J. L. Silva-Filho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

C. C. Judice· 2 shared A. A. Pinheiro· 1 shared A. C. A. V. Kayano· 1 shared A. Chandrasekar· 1 shared A. I. Abdi· 1 shared A. R. R. Freitas· 1 shared A. R. Vago· 1 shared B. Orindi· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersMicrobiology

C. C. Judice

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Plasmodium falciparum adapts its investment into replication versus transmission according to the host environment

A. I. Abdi, F. Achcar, L. Sollelis, J. L. Silva-Filho, K. Mwikali, M. Muthui, S. Mwangi, H. W. Kimingi, B. Orindi, C. Andisi, M. Alkema, A. Chandrasekar, P. Bull, P. Bejon, K. Modrzynska, , M. Marti

The paper shows that Plasmodium falciparum adjusts its investment between replication and transmission based on host factors and changing transmission environments.

bioRxiv · Nov 29, 2022Microbiology

Gas6 drives Zika virus-induced neurological complications in humans and congenital syndrome in immunocompetent mice

J. L. Silva-Filho, The Zika-Unicamp Network, L. G. Oliveira, L. Monteiro, P. L. Parise, N. G. Zanluqui, C. M. Polonio, C. L. Freitas, D. A. Toledo-Teixeira, W. M. Souza, N. Bittencourt, M. R. Amorim, J. Forato, S. P. Muraro, G. F. Souza, , J. L. Proenca-Modena

This study shows Gas6 promotes ZIKV replication and severity in humans and mice, linking it to neurological complications and congenital malformations.

bioRxiv · Jan 27, 2021Microbiology

Malaria in Pregnancy Regulates P-glycoprotein (P-gp/Abcb1a) and ABCA1 Efflux Transporters in the Mouse Visceral Yolk Sac

L. M. Martinelli, K. N. Fontes, M. W. Reginatto, C. B. Andrade, V. R. Monteiro, H. R. Gomes, J. L. Silva-Filho, A. A. Pinheiro, A. R. Vago, F. R. Almeida, F. F. Bloise, S. G. Matthews, T. M. Ortiga-Carvalho, E. Bloise

This study investigates how malaria in pregnancy affects ABC efflux transporters in the mouse visceral yolk sac, finding altered expression of Abcb1a and reduced Abcg1.

Journal of Cellular and Molecular Medicine · Aug 11, 2020Peer-reviewedPharmacology & Toxicology

Platelet disturbances correlate with endothelial cell activation in uncomplicated Plasmodium vivax malaria

J. C. K. Dos-Santos, J. L. Silva-Filho, C. C. Judice, A. C. A. V. Kayano, J. Aliberti, R. Khouri, D. S. De Lima, H. Nakaya, M. V. G. Lacerda, E. V. De Paula, S. C. P. Lopes, F. T. M. Costa

This study finds that platelet activation correlates with endothelial cell activation in uncomplicated Plasmodium vivax malaria, particularly in a subset of patients.

bioRxiv · Jul 26, 2019Immunology