Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin
H. King, S. Ajay Castro, A. Arunrao Pohane, C. M. Scholte, V. A. Fischetti, N. Korotkova, D. C. Nelson, H. C. Dorfmueller
This study identifies the molecular interaction between the PlyCB CBD of the PlyC endolysin and the pRha backbone of Group A Streptococcus and Streptococcus mutans cell wall polysaccharides.
bioRxiv · Mar 19, 2021Biochemistry