Author

V. A. Fischetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Arunrao Pohane· 1 shared A. Varble· 1 shared B. M. Readnour· 1 shared B. Russo· 1 shared C. M. Scholte· 1 shared C. W. Euler· 1 shared D. C. Nelson· 1 shared E. Campisi· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Arunrao Pohane

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Evolution of Gram+ Streptococcus pyogenes has maximized efficiency of the Sortase A cleavage site

B. M. Readnour, Y. A. Ayinuola, B. Russo, Z. Liang, V. A. Fischetti, V. Ploplis, S. W. Lee, F. J. Castellino

This study shows that the Thr4 residue in the SrtA cleavage site of Streptococcus pyogenes M-protein evolved to ensure efficient SrtA cleavage over non-functional cleavage by LPXTGase, stabilizing the virulence factor on the cell wall.

bioRxiv · Dec 21, 2021 · PreprintMicrobiology

Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin

H. King, S. Ajay Castro, A. Arunrao Pohane, C. M. Scholte, V. A. Fischetti, N. Korotkova, D. C. Nelson, H. C. Dorfmueller

This study identifies the molecular interaction between the PlyCB CBD of the PlyC endolysin and the pRha backbone of Group A Streptococcus and Streptococcus mutans cell wall polysaccharides.

bioRxiv · Mar 19, 2021Biochemistry

Integration of prophages into CRISPR loci remodels viral immunity in Streptococcus pyogenes

A. Varble, E. Campisi, C. W. Euler, J. Fyodorova, J. Rostol, V. A. Fischetti, L. A. Marraffini

This study shows that the {Phi}AP1.1 phage uses an anti-CRISPR protein to temporarily disable CRISPR immunity, then integrates into the CRISPR locus to modulate immunity through spacer deletion and transfer.

bioRxiv · Oct 9, 2020 · PreprintMicrobiology

Human blood exposure to Clostridium perfringens epsilon toxin may shed light on erythrocyte fragility during active multiple sclerosis

V. A. Fischetti, O. E. eleso, K. R. Rumah

This paper investigates how Clostridium perfringens epsilon toxin (ETX) causes human red blood cell (RBC) lysis and links this mechanism to erythrocyte fragility observed in active multiple sclerosis.

bioRxiv · Oct 1, 2019 · PreprintMicrobiology