N. Korotkova

Heterogeneity of the group B streptococcal type VII secretion system and influence on colonization of the female genital tract

This study characterizes the heterogeneity of the T7SS in GBS and shows subtype-specific effects on host colonization and gene expression.

Gestational diabetes augments group B Streptococcus perinatal infection through disruptions in maternal immunity and the vaginal microbiota

This study shows that gestational diabetes increases GBS perinatal infection by altering maternal immunity and vaginal microbiota, using a murine model.

PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides

This study identifies PplD as a de-N-acetylase that modifies the cell wall linkage unit of streptococcal rhamnopolysaccharides, enhancing resistance to host antimicrobial proteins.

Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin

This study identifies the molecular interaction between the PlyCB CBD of the PlyC endolysin and the pRha backbone of Group A Streptococcus and Streptococcus mutans cell wall polysaccharides.

Modification of cell wall polysaccharide spatially controls cell division in Streptococcus mutans

This study shows that GroP-deficient immature SCCs spatially coordinate AtlA and MapZ localization in S. mutans, ensuring proper cell division and morphology.

PE5-PPE4-EspG3 trimer structure from mycobacterial ESX-3 secretion system gives insight into cognate substrate recognition by ESX systems

The paper presents the crystal structure of a PE5-PPE4-EspG3 trimer from the ESX-3 system, revealing unique interactions and structural dynamics compared to the ESX-5 system.

Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides

The paper identifies a glycerol phosphate modification on streptococcal rhamnose polysaccharides, revealing its role in host-pathogen interactions and vaccine design.

The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A Carbohydrate in Streptococcus pyogenes