Hypoxia Dynamically Regulates DBC1 Ubiquitination and Stability by SIAH2 and OTUD5 in Breast Cancer Progression
Y. Zhu, Q. Liu, Q. Luo, J. Feng, Y. Zhao, L. Liu, B. Ma, H. Cheng, J. Zhang, T. Zhao, C. Mu, L. Chen, H. Lei, Y. Long, J. Su, , Q. Chen
This study identifies hypoxia-regulated ubiquitination of DBC1 by SIAH2 and OTUD5 as a mechanism driving breast cancer progression.
bioRxiv · Jan 11, 2022 · PreprintCell Biology