Author

C. O'Farrelly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Basu· 1 shared A. Naik· 1 shared B. Manley· 1 shared C. F. de Gascun· 1 shared C. Gardiner· 1 shared C. Keane· 1 shared D. D. Houlihan· 1 shared D. Lemanne· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Basu

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Enhanced cytokine responsiveness in natural killer cells from a pilot cohort of uninfected seronegative women exposed to hepatitis C virus contaminated anti-D immunoglobulin

M. W. Robinson, C. Keane, M. Needham, G. Roche, E. Wallace, J. Connell, C. F. de Gascun, A. Naik, L. J. Fanning, C. Gardiner, D. D. Houlihan, C. O'Farrelly

The study examines innate immune mechanisms in ESN individuals exposed to HCV via contaminated anti-D immunoglobulin, finding enhanced NK cell cytokine responsiveness.

bioRxiv · Aug 28, 2019 · PreprintImmunology

Harnessing patient-specific response dynamics to optimize evolutionary therapies for metastatic clear cell renal cell carcinoma - Learning to adapt

I. C. Sorribes, A. Basu, R. Brady, P. M. Enriquez-Navas, X. Feng, J. N. Kather, N. Nerlakanti, R. Stephens, M. Strobl, I. Tavassoly, N. Vitos, D. Lemanne, B. Manley, C. O'Farrelly, H. Enderling

This paper develops a dynamic tumor-immune model to predict patient response to treatment using NLR as a biomarker and simulates optimal therapies for virtual RCC patients.

bioRxiv · Feb 28, 2019 · PreprintCancer Biology