Tyrosyl-DNA phosphodiesterase 1 (TDP1) and SPRTN protease repair histone 3 and topoisomerase 1 DNA-protein crosslinks in vivo
I. Anticevic, C. Otten, L. Vinkovic, L. Jukic, M. Popovic
This study investigates how TDP1 and SPRTN repair DNA-protein crosslinks in vivo, showing distinct roles in resolving histone H3-DPCs and TOP1-DPCs across species.
bioRxiv · Mar 1, 2023 · PreprintCell Biology