F. Corona

Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria

This study identifies nitroxoline's broad antibacterial activity against Gram-negative bacteria, its mode of action involving metal homeostasis and outer membrane disruption, and resistance mechanisms across multiple species.

Pathwise approximations to solving the filtering problem for the stochastic chemostat

This paper establishes the existence and uniqueness of solutions to the filtering problem for the stochastic chemostat and evaluates three numerical approximation methods.

An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular pathogen Chlamydia trachomatis

This study identifies an NlpC/P60 peptidase in Chlamydia trachomatis that recycles peptidoglycan to support cell division, energy recovery, and immune evasion.

Peptidoglycan maturation controls spatiotemporal organisation of outer membrane proteins in Escherichia coli

The paper shows that peptidoglycan maturation regulates the spatiotemporal organization of outer membrane proteins in E. coli by modulating BAM activity and OMP insertion.

The inactivation of enzymes belonging to the central carbon metabolism, a novel mechanism of developing antibiotic resistance

This paper identifies a novel mechanism of antibiotic resistance in Stenotrophomonas maltophilia through the inactivation of central carbon metabolism enzymes, not through known resistance mechanisms like efflux or target modification.

The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes

This study identifies GpsB as a cytosolic adaptor that coordinates cell wall synthesis with the bacterial cell cycle by interacting with multiple enzymes and proteins.

Biolog phenotype microarray: a tool for the identification of multidrug resistance efflux pumps inducers

This paper identifies inducers of two efflux pumps in Stenotrophomonas maltophilia using bioreporters and phenotype microarrays, showing inducers do not rely on efflux pumps for detoxification.