OPTN limits herpes stromal keratitis severity and demyelination through negative regulation of IL-17 and hyperinflammatory T-cell response
J. M. Ames, T. Yadavalli, C. Patil, J. Hopkins, I. Bhattacharya, D. Shukla
The paper investigates how OPTN reduces HSV-1-induced HSK severity and demyelination by suppressing IL-17 and hyperinflammatory T-cell responses in a mouse model.
bioRxiv · Nov 29, 2021 · PreprintImmunology