Author

C. Poulsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Bennett· 1 shared A. Hamann· 1 shared A. Rosace· 1 shared B. von Thulen· 1 shared F. Leenders· 1 shared J. Pawlowska· 1 shared J. Pfeil· 1 shared L. I. Sakhnini· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Bennett

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2 papers

Recent·Most cited

Automated optimisation of solubility and conformational stability of antibodies and proteins

A. Rosace, A. Bennett, M. Oeller, M. M. Mortensen, L. I. Sakhnini, N. Lorenzen, C. Poulsen, P. Sormanni

This study introduces an automated computational method to co-optimize solubility and conformational stability of antibodies, validated on six antibodies with improved developability without affecting antigen-binding.

bioRxiv · May 20, 2022Biochemistry

Prevention of EAE by PEGylated Antigenic Peptide

J. Pfeil, M. Simonetti, U. Lauer, B. von Thulen, P. Durek, C. Poulsen, J. Pawlowska, M. Kroger, R. Krahmer, F. Leenders, U. Hoffmann, A. Hamann

This study shows that PEGylated antigenic peptides can prevent EAE in mice by inducing regulatory T cells, but are ineffective when administered during peak disease.

bioRxiv · Sep 8, 2020Immunology