Spatial transcriptomics using combinatorial fluorescence spectral and lifetime encoding, imaging and analysis
T. Vu, A. Vallmitjana, J. Gu, K. La, Q. Xu, J. Flores, J. Zimak, J. Shiu, L. Hosohama, J. Wu, C. R. Douglas, M. Waterman, A. Ganesan, P. N. Hedde, E. Gratton, W. Zhao
This paper introduces MOSAICA, a spatial transcriptomics technology that combines spectral and lifetime encoding with machine learning to enable highly multiplexed in situ biomarker profiling.
bioRxiv · Jun 22, 2021Bioengineering