Author

J. Shiu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2

Frequent Co-Authors

A. K. Ganesan· 4 shared A. D. Lander· 2 shared C.-F. Chen· 2 shared J. Wu· 2 shared R. Ruiz-Vega· 2 shared A. Armirotti· 1 shared A. Ganesan· 1 shared A. Vallmitjana· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersCancer Biology

A. K. Ganesan

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Author profile →

5 papers

Recent·Most cited

CDC42 Inhibitors Alter Patterns of Vessel Arborization in Skin and Tumors in vivo

L. M. Vuong, S. J. Hachey, J. Shiu, D. F. Xie, N. Salvador, N. Brindani, S. M. Bertozzi, M. Summa, R. Bertorelli, A. Armirotti, R. Pham, V. S. Ku, T. Nguyen, B. Choi, C. C. Hughes, , A. K. Ganesan

This study identifies CDC42 inhibitors that reduce vessel branching in both normal skin and tumors, offering potential for treating skin cancer and angiogenesis-related diseases.

bioRxiv · Apr 9, 2024 · PreprintCancer Biology

Uncovering Minimal Pathways in Melanoma Initiation

H. Xiao, J. Shiu, C.-F. Chen, J. Wu, P. Zhou, S. S. Telang, R. Ruiz-Vega, A. D. Lander, A. K. Ganesan

This study identifies LNM cells as a pre-malignant state in melanoma initiation, showing they pre-exist in normal skin, expand with Braf activation, and contribute to drug resistance.

bioRxiv · Dec 8, 2023Cancer Biology

Non-invasive Imaging Techniques for Monitoring Cellular Response to Treatment in Stable Vitiligo

J. Shiu, G. Lentsch, C. M. Polleys, P. Mobasher, M. Ericson, I. Georgakoudi, A. K. Ganesan, M. Balu

The paper uses imaging techniques to identify early biomarkers of treatment response in vitiligo patients undergoing punch grafting.

bioRxiv · Aug 15, 2023Bioengineering

Spatial transcriptomics using combinatorial fluorescence spectral and lifetime encoding, imaging and analysis

T. Vu, A. Vallmitjana, J. Gu, K. La, Q. Xu, J. Flores, J. Zimak, J. Shiu, L. Hosohama, J. Wu, C. R. Douglas, M. Waterman, A. Ganesan, P. N. Hedde, E. Gratton, W. Zhao

This paper introduces MOSAICA, a spatial transcriptomics technology that combines spectral and lifetime encoding with machine learning to enable highly multiplexed in situ biomarker profiling.

bioRxiv · Jun 22, 2021Bioengineering

Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes

R. Ruiz-Vega, C.-F. Chen, E. Razzak, P. Vasudeva, T. Krasieva, J. Shiu, M. G. Caldwell, H. Yan, J. Lowengrub, A. K. Ganesan, A. D. Lander

The paper investigates nevus growth arrest using a mouse model and finds that collective cell behavior, not cell-autonomous senescence, explains nevus size control.

bioRxiv · Jul 14, 2020Cancer Biology