Author

C. R. Garland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. A. Leib· 3 shared C. D. Patel· 2 shared I. M. Backes· 2 shared M. E. Ackerman· 2 shared S. A. Taylor· 2 shared A. B. Balazs· 1 shared A. J. Dutton· 1 shared B. K. Byrd· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

D. A. Leib

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Asymptomatic neonatal herpes simplex virus infection in mice leads to long-term cognitive impairment

A. J. Dutton, C. D. Patel, S. A. Taylor, C. R. Garland, E. Turnbaugh, R. Alers-Velazquez, J. Mehrbach, K. M. Nautiyal, D. A. Leib

This study shows that asymptomatic neonatal HSV infection in mice causes long-term cognitive impairment, highlighting the role of the γ34.5 gene in neurovirulence.

bioRxiv · Apr 22, 2024 · PreprintMicrobiology

Antibody effector functions are required for broad and potent protection of neonates from herpes simplex virus infection

M. D. Slein, I. M. Backes, C. R. Garland, N. S. Kelkar, D. A. Leib, M. E. Ackerman

This study shows that both neutralization and effector functions of antibodies are needed for effective protection against neonatal HSV-1, while effector functions alone suffice for HSV-2.

bioRxiv · Aug 29, 2023 · PreprintImmunology

Maternally transferred monoclonal antibodies protect neonatal mice from herpes simplex virus-induced mortality and morbidity

I. M. Backes, B. K. Byrd, C. D. Patel, S. A. Taylor, C. R. Garland, S. W. MacDonald, A. B. Balazs, S. C. Davis, M. E. Ackerman, D. A. Leib

This study shows that HSV-specific monoclonal antibodies transferred from mothers or directly administered to neonatal mice reduce HSV-induced mortality and morbidity.

Journal of Experimental Medicine · Sep 26, 2022Peer-reviewedImmunology