Author

C. R. Wagner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

O. Kilic· 2 shared Y. Wang· 2 shared A. A. Almotlak· 1 shared C. Lichtenfels· 1 shared D. A. Largaespada· 1 shared E. Mews· 1 shared J. M. Siegfried· 1 shared J. Petersburg· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioengineering

O. Kilic

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Multivalent, Bispecific ????B7-H3-????CD3 Chemically Self-Assembled Nanorings Direct Potent T-cell Responses Against Medulloblastoma

E. Mews, P. J. Beckmann, M. Patchava, Y. Wang, D. A. Largaespada, C. R. Wagner

This paper designs and tests bispecific nanorings targeting B7-H3 and CD3 to enhance T-cell responses against medulloblastoma, showing improved tumor infiltration and reduced toxicity.

bioRxiv · Mar 15, 2022Cancer Biology

Macro-Chemical Biology: Engineering Biomimetic Trogocytosis with Farnesylated Chemically Self-Assembled Nanorings

Y. Wang, L. Rozumalski, C. Lichtenfels, J. Petersburg, O. Kilic, M. Distefano, C. R. Wagner

This paper introduces a biomimetic trogocytosis platform using farnesylated chemically self-assembled nanorings to enable directional cargo transfer between cells.

bioRxiv · Mar 1, 2022 · PreprintBioengineering

Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T cell Mediated Anti-Tumor Response and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression

O. Kilic, M. R. Matos de Souza, A. A. Almotlak, J. M. Siegfried, C. R. Wagner

This paper demonstrates that EGFR-targeting fibronectin-based PARs suppress tumor growth in vivo by modulating the tumor microenvironment and reducing PD-1/PD-L1 expression.

bioRxiv · Apr 22, 2020Bioengineering