Activation of the actin/MRTF-A/SRF signalling pathway in pre-malignant mammary epithelial cells by P-cadherin is essential for transformation
L. Faria, S. Canato, T. T. Jesus, M. Goncalves, P. S. Guerreiro, C. S. Lopes, I. Meireles, E. Morais-de-Sa, J. Paredes, F. Janody
This study identifies P-cadherin's role in activating the actin/MRTF-A/SRF pathway in pre-malignant mammary cells, essential for early breast cancer progression.
bioRxiv · Feb 26, 2022 · PreprintCancer Biology