Author

Z. Werb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

V. Sitarama· 2 shared A. Abbasi· 1 shared A. Barczak· 1 shared A. C. Nelson· 1 shared A. Chauhan· 1 shared A. Detweiler· 1 shared A. Goga· 1 shared A. Nanjaraj· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

V. Sitarama

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dissecting the contributions of tumor heterogeneity on metastasis at single-cell resolution

J. Winkler, W. Tan, C. M. M. Diadhiou, C. S. McGinnis, A. Abbasi, S. Hasnain, S. Durney, E. Atamaniuc, D. Superville, L. Awni, J. V. Lee, J. H. Hinrichs, M. Y. Hein, M. Borja, A. Detweiler, , Z. Werb

This study analyzes single-cell transcriptomes of primary tumors and metastases from breast cancer models, identifying transcriptional differences and gene signatures linked to metastatic potential and patient outcomes.

bioRxiv · Aug 4, 2022 · PreprintCancer Biology

Fine-tuning of Epithelial EGFR signals Supports Coordinated Mammary Gland Development

A. Samocha, H. Doh, V. Sitarama, Q. Nguyen, O. Gbenedio, J. Rudolf, W. Eckalbar, A. Barczak, Y. Miao, C. Garcia, D. Lawson, Z. Werb, K. Kessenbrock, P. Depeille, J. Roose

This study shows that Rasgrp1 fine-tunes EGFR signals in mammary epithelial cells to regulate development during puberty, with in vitro and in vivo effects on proliferation, branching, and cellularity.

bioRxiv · Sep 10, 2020 · PreprintCell Biology

Inflammation promotes tumor aggression by stimulating stromal cell-dependent collagen crosslinking and stromal stiffening

O. Maller, A. P. Drain, A. S. Barrett, S. Borgquist, B. Ruffell, P. T. Thanh, T. Gruosso, H. Kuasne, J. N. Lakins, I. Acerbi, J. M. Barnes, T. Nemkov, A. Chauhan, J. Gruenberg, A. Nasir, , V. M. Weaver

This study shows that inflammation promotes tumor aggression by stimulating stromal cell-dependent collagen crosslinking and stiffening, identifying lysyl hydroxylase two as a biomarker.

bioRxiv · Feb 13, 2020Cancer Biology