Engineering, Generation and Preliminary Characterization of a Humanized Porcine Sickle Cell Disease Animal Model
T. M. Franks, S. J. Haugabook, E. A. Ottinger, M. S. Vermillion, K. M. Pawlik, T. M. Townes, C. S. Rogers
The paper describes the development and initial characterization of a humanized porcine sickle cell disease model that expresses human globin genes under porcine regulatory regions.
bioRxiv · Sep 15, 2020 · PreprintPhysiology