Author

C. Saikia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

E. Reuveny· 2 shared I. Karbat· 2 shared A. Goldenzweig· 1 shared D. Gordon· 1 shared H. Altman-Gueta· 1 shared J. J. Weinstein· 1 shared O. Dym· 1 shared S. J. Fleishman· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

E. Reuveny

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2 papers

Recent·Most cited

One-shot design elevates functional expression levels of a voltage-gated potassium channel

J. J. Weinstein, C. Saikia, I. Karbat, A. Goldenzweig, E. Reuveny, S. J. Fleishman

The paper introduces mPROSS, an algorithm that improves the functional expression of membrane proteins through one-shot design, achieving up to 14-fold increase in current densities without altering single-channel activity.

bioRxiv · Dec 28, 2022Biochemistry

A molecular lid mechanism of K+ channelblocker action revealed by a cone peptide

C. Saikia, O. Dym, H. Altman-Gueta, D. Gordon, E. Reuveny, I. Karbat

The paper investigates two cone peptides' mechanisms of blocking K+ channels in Drosophila Shaker, revealing a 'molecular lid' mechanism for one peptide.

bioRxiv · Jun 15, 2020Pharmacology & Toxicology