Into the deep (sequence) of the foot-and-mouth disease virus gene pool: bottlenecks and adaptation during infection in naïve and vaccinated cattle
I. Fish, C. Stenfeldt, R. Palinski, S. J. Pauszek, J. Arzt
This study analyzes FMDV quasispecies dynamics in vaccinated and non-vaccinated cattle, finding vaccination leads to early bottlenecks and reduced viral diversity, while non-vaccinated animals show more genetic diversity and adaptation.
bioRxiv · Nov 21, 2019Microbiology